I have a question about how to combine student t test results after multiple imputations. In sasstat software, mi is done using the mi and mianalyze procedures in conjunction with other standard analysis procedures e. This method involves 3 steps, creating multiple imputed data sets, carrying out. Multiple imputation mi is a technique for handling missing data. Hi, i have looked into a lot of documentation from and papers from other authors but i dont seem to find how to use the minimum statement for the fcs statement part of proc mi.
The first 150 observations will have imputation 1, the next 150 have imputation 2, and so on. Imputation methods this section describes the methods for multiple imputation that are available in the mi procedure. For each imputation, the data set contains all variables in the input data set, with missing values being replaced by the imputed values. Dec 04, 2017 mean imputation replaces missing data in a numerical variable by the mean value of the nonmissing values. The proposed method will produce the same posterior predictive distribution for the missing data as tang 2015, 2016 mda algorithm. The scaler values are obtained by using the rubins rule of combining estimates. When this program runs it will produce a large new dataset with 5. This book will be helpful to researchers looking for guidance on the use of multiple imputation to address missing data problems, along with. This sas callable program is called iveware written by raghunathan et al. Procedure multiple imputation analyzer proc mianalyze is used after proc mi to be able to combine estimates from the results of analyzing multiply imputed data sets.
Imputation techniques using sas software for incomplete. When this program runs it will produce a large new dataset with 5 number of observations in a dataset. The multiply imputed data sets are then analyzed by using standard procedures. A marriage of the mi and copula procedures zhixin lun, ravindra khattree, oakland university abstract missing data is a common phenomenon in various data analyses. The most effective we consider only the multiple imputation techniques 6 that are techniques were applied to diabetes clinical trial data. Multiple imputation for missing data statistics solutions. Multiple imputation using sas software article pdf available in journal of statistical software 456 december 2011 with 879 reads how we measure reads. More specifically, i have a data set of continuous and discrete variables. This article shows how to perform mean imputation in sas. Hi, i have looked into a lot of documentation from sas. In multiple imputation, each missing datum is replaced by m1 simulated values. The software on this page is available for free download, but is not supported by the methodology centers helpdesk. Likelihood ratio testing after multiple imputation statalist. I examine two approaches to multiple imputation that have been incorporated into widely available software.
In such a case, understanding and accounting for the hierarchical structure of the data can be challenging, and tools to handle these types of data are relatively rare. These problems are discussed further in my next blog post. Jan 01, 2014 multiple imputation is implemented in several software packages such as stata 10. Sas software seems to be lagging the state of the art in imputation by about a decade i think their last serious improvement for imputation was when they added proc mi to sasstat about ten years ago and that methodology had already been around for twenty years at that time.
Imputation is a flexible method for handling missingdata problems since it efficiently uses all the available information in the data. Most experts agree that the drawbacks far outweigh the advantages, especially since most software supports modern alternatives to single imputation, such as multiple imputation. Appropriate multiple imputation and analytic methods are evaluated and demonstrated through an analysis application using longitudinal survey data with missing data issues. The r implementation of chained equations does this as does the sas implementation of norm proc mi. These multiply imputed data sets are then analyzed by using standard procedures for complete data. Spss will do missing data imputation and analysis, but, at least for me, it takes some getting used to. Little and rubin 1987, 1990 contend that, with standard statistical techniques, there are.
The following is the code written for sas version 8. Jun 29, 2015 multiple imputation using spss david c. However i will also provide the script that results from what i do. Nick has a paper in the american statistician warning about bias in multiple imputation arising from rounding data imputed under a normal assumption. In this post, i show and explain how to conduct mi for threelevel and crossclassified data. Abstract multiple imputation provides a useful strategy for dealing with data sets that have missing values.
Outsasdataset creates an output sas data set in which to put the imputation results. Checklist of issues and considerations for the multiple imputation process. The mi and mianalyze procedures, which were introduced as experimental software in releases 8. Instead of filling in a single value for each missing value, a multiple imputation procedure replaces each missing value with a set of plausible values that represent the uncertainty about the right value to. Mean imputation does not preserve relationships between variables such as correlations. Pdf software for the handling and imputation of missing. A statistical programming story chris smith, cytel inc. Multiple imputation and multiple regression with sas and ibm spss. Multiple imputation of missing data using sas, berglund. Which statistical program was used to conduct the imputation. Using spss to handle missing data university of vermont. The multiple imputation process contains three phases. The mi procedure in the sasstat software is a multi. Multiple imputation for variables following the multivariate normal distribution is supported by programs as norm schafer, 1999, splus 6 for windows 2006, and sas 8.
Multiple imputation using sas software multiple imputation provides a useful strategy for dealing with data sets that have missing values. May 29, 2012 nick has a paper in the american statistician warning about bias in multiple imputation arising from rounding data imputed under a normal assumption. That is not a very new program, but it works nicely and until they revise it, it is. In this chapter, i provide stepbystep instructions for performing multiple imputation with schafers 1997 norm 2. Download pdf multiple imputation of missing data using sas.
Can i get just one p value by combining multiple t test results. Instead of attempting to estimate each value and using these estimates to predict the parameters, this method draws a random sample of the missing values from its distribution. Multiple imputation and multiple regression with sas and. It also presents three statistical drawbacks of mean imputation. Berglund, university of michiganinstitute for social research abstract this presentation emphasizes use of sas 9. Modern imputation methods have become widely available for practitioners through software products such as splus 6. Multiple imputation for continuous and categorical data. Multiple imputations of categorical variables can be created using the loglinear model schafer 1997, which is implemented in the missing data library of s. We are not advocating in favor of any one technique to handle missing data and depending. This method involves 3 steps, creating multiple imputed data. The idea of multiple imputation for missing data was first proposed by rubin 1977. In this method the imputation uncertainty is accounted for by creating these multiple datasets. It offers practical instruction on the use of sas for multiple imputation and provides numerous examples that use a variety of public release data sets. For data sets with monotone missing patterns, either a parametric regression method rubin 1987 that assumes multivariate normality or a nonparametric method that uses.
I couldnt find an example from sas documentation, though sas did provide samples on how to combine results from regression analysis or mixed model analysis by using the mianalyze procedure. For example, you have 150 observations in a dataset. Handling missing values with sas university of iowa sas. Oct 30, 20 statistical analysis system sas release 8. The software also allows for weights to account for sampling design both at level 1 and level 2. Multiple imputation of incomplete multivariate data under a normal model. Multiple imputation mi of missing values in hierarchical data can be tricky when the data do not have a simple twolevel structure. In the last decade, substantial progress has been made on methods for imputation of missing data. Proc mi in sas, norm package in r that provide missing data imputation for incomplete multivariate normal data. There is also a very important package in the form of sas macro for multiple imputation using a. Multiple imputation for threelevel and crossclassified data. Multiple imputation was not originally designed to give good predictions see the discussion and literature in mi predict or a good overall fit, which is usually what one tries to asses when asking about the better model whatever that means rich has asked this crucial question. The imputation methods were compared on simulated data to assess preciseness. Pmms and deltaadjusted pmms by building on existing software packages e.
Columnwise speci cation of the imputation model section3. A comparison of sas, stata, iveware, and r patricia a. Rubin 1987 book on multiple imputation schafer 1997 book on mcmc and multiple imputation for missingdata problems more subjectoriented carpenter, j. Dec 04, 2017 mean imputation does not preserve relationships between variables such as correlations. Missing data, multiple imputation and associated software. The mi procedure in the sasstat software is a multiple imputation procedure that creates. This sascallable program is called iveware written by raghunathan et al. The method of choice depends on the pattern of missingness in the data and the type of the imputed variable, as summarized in table 77. There is also a very important package in the form of sas macro for multiple imputation using a sequences of regression models. This book will be helpful to researchers looking for guidance on the use of multiple imputation to address missing data problems, along with examples of correct analysis techniques. Because i used norm to analyze the data file on behavior problems of children with of cancer patients in what i have called part 2 of the missing data page, i will use a different data file here. Using sas for multiple imputation and analysis of data presents use of sas to address missing data issues and analysis of longitudinal data. Multiple imputation for missing data is an attractive method for handling missing data in multivariate analysis. Although these instructions apply most directly to norm, most of the concepts apply to other mi programs as well.
With norm a multiple imputation can be implemented. The second procedure runs the analytic model of interest here it is a linear regression using proc glm within each of the imputed datasets. Most multiple imputation procedures involve iterative schemes either to get the parameters or to cycle round the variables. Multiple imputation using sas software yang yuan sas institute inc. Practical suggestions on rounding in multiple imputation. Below are tables of the means and standard deviations of the four variables in our. Because spss works primarily through a gui, it is easiest to present it that way. Multiple imputation using sas software yuan journal of. Appropriate multiple imputation and analytic methods are evaluated and demonstrated through an analysis application using. Often, the analyst is tempted to rush into multiple imputation without a complete understanding of the missing data problem and associated issues. The paper presents sas procedures, proc mi and proc mianalyze, for creating multiple imputations for incomplete multivariate data and for analyzing results from multiply imputed data sets. Features this paper describes the r package mice 2. Statacorp, 2007, the mice library in splus 2007, spss 19.
After imputations are complete, imputed values within 1 5 can be rounded to 0, and values within. Multiple imputation is implemented in several software packages such as stata 10. Roles of imputation methods for filling the missing values. Imputation techniques using sas software for incomplete data. The first is proc mi where the user specifies the imputation model to be used and the number of imputed datasets to be created. Multiple imputation is the last strategy that will be discussed. Multiple imputation an overview sciencedirect topics. The checklist presented in table 1 is a suggested guide for planning the multiple imputation project. In sas, proc mi is used to replace missing values with multiple imputation. Iveware can be used under windows, linux, and mac, and with software packages like sas, spss, stata, and r, or as a standalone tool. We have selected sas for this examplewithout recommending it over other alternativesbecause it is a commonly used generalpurpose. Jan 02, 2019 multiple imputation mi of missing values in hierarchical data can be tricky when the data do not have a simple twolevel structure.
Mi is becoming an increasingly popular method for sensitivity analyses in order to assess the impact of missing data. The data set includes an identification variable, imputation, to identify the imputation number. The mi procedure in sasstat software is a multiple imputation. Instead of lling in a single value for each missing value, a multiple imputation procedure replaces each missing value with a set of plausible values that represent the. Multiple imputation is a simulationbased approach to the statistical analysis of incomplete data. Missing data takes many forms and can be attributed to many causes. Multiple imputation using sas software journal of statistical. Multiple imputation as a valid way of dealing with. In multiple imputation, the imputatin process is repeated multiple times resulting in multiple imputed datasets. Sas software seems to be lagging the state of the art in imputation by about a decade i think their last serious improvement for imputation was when they added proc mi to sas stat about ten years ago and that methodology had already been around for twenty years at that time. Multiple imputation using the fully conditional specification method. One example where you might run afoul of this is if the data are truly dichotomous or count variables, but you model it as normal either because your software is unable to model dichotomous values directly or because you prefer the theoretical. The results from the m complete data sets are com bined for the inference.